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The Effect of Phosphatidylserine on a pH-Responsive Peptide Is Defined by Its Noninserting End

The acidity-triggered rational membrane (ATRAM) peptide was designed to target acidic diseases such as cancer. An acidic extracellular medium, such as that found in aggressive tumors, drives the protonation of the glutamic acids in ATRAM, leading to the membrane translocation of its C-terminus and t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Nguyen, Vanessa P., Dixson, Andrew C., Barrera, Francisco N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712489/
https://ncbi.nlm.nih.gov/pubmed/31400916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.023
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