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Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding
The aggregation and deposition of tau is a hallmark of a class of neurodegenerative diseases called tauopathies. Despite intensive study, cellular and molecular factors that trigger tau aggregation are not well understood. Here, we provide evidence for two mechanisms relevant to the initiation of ta...
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| 出版年: | Biophys J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712485/ https://ncbi.nlm.nih.gov/pubmed/31400913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.028 |
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