Mechanistic insights into the protective roles of polyphosphate against amyloid cytotoxicity

The universally abundant polyphosphate (polyP) accelerates fibril formation of disease-related amyloids and protects against amyloid cytotoxicity. To gain insights into the mechanism(s) by which polyP exerts these effects, we focused on α-synuclein, a well-studied amyloid protein, which constitutes...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Lempart, Justine, Tse, Eric, Lauer, James A, Ivanova, Magdalena I, Sutter, Alexandra, Yoo, Nicholas, Huettemann, Philipp, Southworth, Daniel, Jakob, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751573/
https://ncbi.nlm.nih.gov/pubmed/31533964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900486
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