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Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding
The aggregation and deposition of tau is a hallmark of a class of neurodegenerative diseases called tauopathies. Despite intensive study, cellular and molecular factors that trigger tau aggregation are not well understood. Here, we provide evidence for two mechanisms relevant to the initiation of ta...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712485/ https://ncbi.nlm.nih.gov/pubmed/31400913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.028 |
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