Á lódáil...

Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding

The aggregation and deposition of tau is a hallmark of a class of neurodegenerative diseases called tauopathies. Despite intensive study, cellular and molecular factors that trigger tau aggregation are not well understood. Here, we provide evidence for two mechanisms relevant to the initiation of ta...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Biophys J
Main Authors: Wickramasinghe, Sanjula P., Lempart, Justine, Merens, Hope E., Murphy, Jacob, Huettemann, Philipp, Jakob, Ursula, Rhoades, Elizabeth
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712485/
https://ncbi.nlm.nih.gov/pubmed/31400913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.028
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!