Significantly increased anti‐tumor activity of carcinoembryonic antigen‐specific chimeric antigen receptor T cells in combination with recombinant human IL‐12

BACKGROUND AIMS: Chimeric antigen receptor T cells (CAR‐T cells) have been successfully used in treatments of hematological tumors, however, their anti‐tumor activity in solid tumor treatments was limited. As IL‐12 increases T‐cell immune functions, we designed carcinoembryonic antigen (CEA) specifi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Med
Egile Nagusiak: Chi, Xiaowei, Yang, Peiwei, Zhang, Erhao, Gu, Jieyi, Xu, Hui, Li, Mengwei, Gao, Xinmei, Li, Xin, Zhang, Yinan, Xu, Hanmei, Hu, Jialiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Cancer Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712469/
https://ncbi.nlm.nih.gov/pubmed/31237116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2361
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