Significantly increased anti‐tumor activity of carcinoembryonic antigen‐specific chimeric antigen receptor T cells in combination with recombinant human IL‐12

BACKGROUND AIMS: Chimeric antigen receptor T cells (CAR‐T cells) have been successfully used in treatments of hematological tumors, however, their anti‐tumor activity in solid tumor treatments was limited. As IL‐12 increases T‐cell immune functions, we designed carcinoembryonic antigen (CEA) specifi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Med
Hlavní autoři: Chi, Xiaowei, Yang, Peiwei, Zhang, Erhao, Gu, Jieyi, Xu, Hui, Li, Mengwei, Gao, Xinmei, Li, Xin, Zhang, Yinan, Xu, Hanmei, Hu, Jialiang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712469/
https://ncbi.nlm.nih.gov/pubmed/31237116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2361
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky