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Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors

The potential for adoptive cell immunotherapy as a treatment against cancers has been demonstrated by the remarkable response in some patients with hematological malignancies using autologous T cells endowed with chimeric antigen receptors (CARs) specific for CD19. Clinical efficacy of CAR-T cell th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Zhang, Erhao, Gu, Jieyi, Xu, Hanmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767005/
https://ncbi.nlm.nih.gov/pubmed/29329591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0759-3
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