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Chimeric antigen receptor T-cell therapy for solid tumors

Chimeric antigen receptor (CAR) T cells are engineered constructs composed of synthetic receptors that direct T cells to surface antigens for subsequent elimination. Many CAR constructs are also manufactured with elements that augment T-cell persistence and activity. To date, CAR T cells have demons...

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Bibliographic Details
Published in:Mol Ther Oncolytics
Main Authors: Newick, Kheng, Moon, Edmund, Albelda, Steven M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849432/
https://ncbi.nlm.nih.gov/pubmed/27162934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.6
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