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Protein Engineering through Tandem Transamidation

Semisynthetic proteins engineered to contain non-coded elements such as post-translational modifications (PTMs) represent a powerful class of tools for interrogating biological processes. Here, we introduce a one-pot, chemoenzymatic method that allows broad access to chemically modified proteins. Th...

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Foilsithe in:Nat Chem
Main Authors: Thompson, Robert E., Stevens, Adam J., Muir, Tom. W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711197/
https://ncbi.nlm.nih.gov/pubmed/31263208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0281-2
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