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A promiscuous split intein with expanded protein engineering applications
The protein trans-splicing (PTS) activity of naturally split inteins has found widespread use in chemical biology and biotechnology. However, currently used naturally split inteins suffer from an “extein dependence,” whereby residues surrounding the splice junction strongly affect splicing efficienc...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5559002/ https://ncbi.nlm.nih.gov/pubmed/28739907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701083114 |
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