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An Atypical Mechanism of Split Intein Molecular Recognition and Folding

Split inteins associate to trigger protein splicing in trans, a posttranslational modification in which protein sequences fused to the intein pair are ligated together in a traceless manner. Recently, a family of naturally split inteins has been identified that is split at a non-canonical location i...

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Publicat a:J Am Chem Soc
Autors principals: Stevens, Adam J., Sekar, Giridhar, Gramespacher, Josef A., Cowburn, David, Muir, Tom W.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232844/
https://ncbi.nlm.nih.gov/pubmed/30156841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07334
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