Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first step in the kynurenine pathway of tryptophan (Trp) degradation that produces several biologically active Trp metabolites. L-kynurenine (Kyn), the first byproduct by IDO1, promotes immunoregulatory effects via activation of the Aryl hydrocarbon...

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Argitaratua izan da:Front Immunol
Egile Nagusiak: Gargaro, Marco, Vacca, Carmine, Massari, Serena, Scalisi, Giulia, Manni, Giorgia, Mondanelli, Giada, Mazza, Emilia M. C., Bicciato, Silvio, Pallotta, Maria T., Orabona, Ciriana, Belladonna, Maria L., Volpi, Claudia, Bianchi, Roberta, Matino, Davide, Iacono, Alberta, Panfili, Eleonora, Proietti, Elisa, Iamandii, Ioana Maria, Cecchetti, Violetta, Puccetti, Paolo, Tabarrini, Oriana, Fallarino, Francesca, Grohmann, Ursula
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710348/
https://ncbi.nlm.nih.gov/pubmed/31481962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01973
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