IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1

The cytokine interleukin IL‐35 is known to exert strong immunosuppressive functions. Indoleamine 2,3‐dioxygenase 1 (IDO1) and Arginase 1 (Arg1) are metabolic enzymes that, expressed by dendritic cells (DCs), contribute to immunoregulation. Here, we explored any possible link between IL‐35 and the ac...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Panfili, Eleonora, Mondanelli, Giada, Orabona, Ciriana, Bianchi, Roberta, Gargaro, Marco, Fallarino, Francesca, Puccetti, Paolo, Grohmann, Ursula, Volpi, Claudia, Belladonna, Maria Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Short Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484402/
https://ncbi.nlm.nih.gov/pubmed/30793469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14215
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