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A Defect in Tryptophan Catabolism Impairs Tolerance in Nonobese Diabetic Mice
The predisposition of nonobese diabetic (NOD) mice to develop autoimmunity reflects deficiencies in both peripheral and central tolerance. Several defects have been described in these mice, among which aberrant antigen-presenting cell function and peroxynitrite formation. Prediabetes and diabetes in...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196078/ https://ncbi.nlm.nih.gov/pubmed/12835483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030633 |
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