Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

Indoleamine 2,3-dioxygenase (IDO1), a tryptophan catabolizing enzyme, is recognized as an authentic regulator of immunity in several physiopathologic conditions. We have recently demonstrated that IDO1 does not merely degrade tryptophan and produce immunoregulatory kynurenines, but it also acts as a...

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Bibliografiske detaljer
Main Authors: Pallotta, Maria Teresa, Orabona, Ciriana, Bianchi, Roberta, Vacca, Carmine, Fallarino, Francesca, Belladonna, Maria Laura, Volpi, Claudia, Mondanelli, Giada, Gargaro, Marco, Allegrucci, Massimo, Talesa, Vincenzo Nicola, Puccetti, Paolo, Grohmann, Ursula
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193887/
https://ncbi.nlm.nih.gov/pubmed/25215657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12360
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