Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

Indoleamine 2,3-dioxygenase (IDO1), a tryptophan catabolizing enzyme, is recognized as an authentic regulator of immunity in several physiopathologic conditions. We have recently demonstrated that IDO1 does not merely degrade tryptophan and produce immunoregulatory kynurenines, but it also acts as a...

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Bibliografische gegevens
Hoofdauteurs: Pallotta, Maria Teresa, Orabona, Ciriana, Bianchi, Roberta, Vacca, Carmine, Fallarino, Francesca, Belladonna, Maria Laura, Volpi, Claudia, Mondanelli, Giada, Gargaro, Marco, Allegrucci, Massimo, Talesa, Vincenzo Nicola, Puccetti, Paolo, Grohmann, Ursula
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193887/
https://ncbi.nlm.nih.gov/pubmed/25215657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12360
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