Thrombospondin-2 regulates extracellular matrix production, LOX levels, and cross-linking via downregulation of miR-29

Collagen fibrillogenesis and crosslinking have long been implicated in extracellular matrix (ECM)-dependent processes such as fibrosis and scarring. However, the extent to which matricellular proteins influence ECM protein production and fibrillar collagen crosslinking has yet to be determined. Here...

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Publicado no:Matrix Biol
Main Authors: Calabro, N.E., Barrett, A., Chamorro-Jorganes, A., Tam, S., Kristofik, N.J., Hao, Xing, Loye, Ayomipose M., Sessa, W.C., Hansen, K., Kyriakides, T.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710120/
https://ncbi.nlm.nih.gov/pubmed/30876926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2019.03.002
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