Thrombospondin-1 Is Downregulated by Anoxia and Suppresses Tumorigenicity of Human Glioblastoma Cells

Angiogenesis, the sprouting of new capillaries from preexisting blood vessels, results from a disruption of the balance between stimulatory and inhibitory factors. Here, we show that anoxia reduces expression of thrombospondin-1 (TSP-1), a natural inhibitor of angiogenesis, in glioblastoma cells. Th...

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Bibliografiska uppgifter
Huvudupphovsmän: Tenan, Mirna, Fulci, Giulia, Albertoni, Michele, Diserens, Annie-Claire, Hamou, Marie-France, El Atifi-Borel, Michèle, Feige, Jean-Jacques, Pepper, Michael S., Van Meir, Erwin G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2000
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193158/
https://ncbi.nlm.nih.gov/pubmed/10811871
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