Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice

Interactions between collagenous extracellular matrices and von Willebrand factor (VWF) are critical for hemostasis and thrombosis. In the present study, we investigated the contribution of an extracellular matrix (ECM) abnormality to the bleeding diathesis in thrombospondin-2 (TSP2) knockout (KO) m...

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Publicado en:Blood
Main Authors: Kristofik, Nina, Calabro, Nicole E., Tian, Weiming, Meng, Aaron, MacLauchlan, Susan, Wang, Yinong, Breuer, Christopher K., Tellides, George, Niklason, Laura E., Kyriakides, Themis R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Thrombosis and Hemostasis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034742/
https://ncbi.nlm.nih.gov/pubmed/27471233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-702845
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