The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

Senescent cells secrete inflammatory cytokines, proteases, and other factors, which are indicated as senescence-associated secretory phenotype (SASP). There are contrasting studies on the role of the SASP in cancer. Studies suggested that cancer cells may misuse the senescent secretome for their gro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Alessio, Nicola, Aprile, Domenico, Squillaro, Tiziana, Di Bernardo, Giovanni, Finicelli, Mauro, Melone, Mariarosa AB, Peluso, Gianfranco, Galderisi, Umberto
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2019
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710033/
https://ncbi.nlm.nih.gov/pubmed/31412320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102172
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