The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

Senescent cells secrete inflammatory cytokines, proteases, and other factors, which are indicated as senescence-associated secretory phenotype (SASP). There are contrasting studies on the role of the SASP in cancer. Studies suggested that cancer cells may misuse the senescent secretome for their gro...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Alessio, Nicola, Aprile, Domenico, Squillaro, Tiziana, Di Bernardo, Giovanni, Finicelli, Mauro, Melone, Mariarosa AB, Peluso, Gianfranco, Galderisi, Umberto
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710033/
https://ncbi.nlm.nih.gov/pubmed/31412320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102172
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