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Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells

A sharp definition of what a senescent cell is still lacking since we do not have in depth understanding of mechanisms that induce cellular senescence. In addition, senescent cells are heterogeneous, in that not all of them express the same genes and present the same phenotype. To further clarify th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Capasso, Stefania, Alessio, Nicola, Squillaro, Tiziana, Di Bernardo, Giovanni, Melone, Mariarosa A., Cipollaro, Marilena, Peluso, Gianfranco, Galderisi, Umberto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741838/
https://ncbi.nlm.nih.gov/pubmed/26540573
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