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The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance

As a contributor to multidrug resistance, the family of multidrug and toxin extrusion (MATE) transporters couples the efflux of chemically dissimilar compounds to electrochemical ion gradients. Although divergent transport mechanisms have been proposed for these transporters, previous structural and...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Jagessar, Kevin L., Mchaourab, Hassane S., Claxton, Derek P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709631/
https://ncbi.nlm.nih.gov/pubmed/31289123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009195
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