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Structural insights into H(+)-coupled multidrug extrusion by a MATE transporter
Multidrug and toxic compound extrusion (MATE) transporters contribute to multidrug resistance by coupling the efflux of drugs to the influx of Na(+) or H(+). Known structures of Na(+)-coupled, extracellular-facing MATE transporters from the NorM subfamily revealed twelve membrane-spanning segments r...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825517/ https://ncbi.nlm.nih.gov/pubmed/24141706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2687 |
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