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Sodium and proton coupling in the conformational cycle of a MATE antiporter from Vibrio cholerae

Secondary active transporters belonging to the multidrug and toxic compound extrusion (MATE) family harness the potential energy of electrochemical ion gradients to export a broad spectrum of cytotoxic compounds, thus contributing to multidrug resistance. The current mechanistic understanding of ion...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Claxton, Derek P., Jagessar, Kevin L., Steed, P. Ryan, Stein, Richard A., Mchaourab, Hassane S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142240/
https://ncbi.nlm.nih.gov/pubmed/29915043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802417115
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