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Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner

PURPOSE: While the effects of high doses of ionizing radiation (IR) are relatively well characterized, the molecular mechanisms underlying cellular responses to prolonged exposure to low doses of radiation remain largely under-investigated. MATERIALS AND METHODS: Here, we addressed the DNA damage an...

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Vydáno v:Int J Radiat Biol
Hlavní autoři: Koturbash, Igor, Merrifield, Matt, Kovalchuk, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709590/
https://ncbi.nlm.nih.gov/pubmed/27758128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2017.1231943
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