Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals

Younger individuals are more prone to develop cancer upon ionizing radiation (IR) exposure. Radiation-induced tumors are associated with inefficient repair of IR-induced DNA damage and genome instability. Phosphorylation of histone H2AX (γ-H2AX) is the initial event in repair of IR-induced DNA damag...

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Detalhes bibliográficos
Main Authors: Hudson, Darryl, Kovalchuk, Igor, Koturbash, Igor, Kolb, Bryan, Martin, Olga A., Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164369/
https://ncbi.nlm.nih.gov/pubmed/21685513
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