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In Vivo Pharmacodynamic Study of Cefiderocol, a Novel Parenteral Siderophore Cephalosporin, in Murine Thigh and Lung Infection Models

The pharmacokinetic (PK) and pharmacodynamic (PD) parameters which correlated with the in vivo efficacy of cefiderocol were evaluated using neutropenic murine thigh and lung infection models in which the infections were caused by a variety of Gram-negative bacilli. The dose fractionation study using...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Nakamura, Rio, Ito-Horiyama, Tsukasa, Takemura, Miki, Toba, Shinsuke, Matsumoto, Shuhei, Ikehara, Tatsuya, Tsuji, Masakatsu, Sato, Takafumi, Yamano, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709502/
https://ncbi.nlm.nih.gov/pubmed/31262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02031-18
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