Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury.

Podocytes have limited ability to recover from injury. Here, we demonstrate that increased mitochondrial biogenesis, to meet the metabolic and energy demand of a cell, accelerates podocyte recovery from injury. Analysis of events induced during podocyte injury and recovery showed marked upregulation...

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Publicado no:Kidney Int
Main Authors: Arif, Ehtesham, Solanki, Ashish K., Srivastava, Pankaj, Rahman, Bushra, Fitzgibbon, Wayne R., Deng, Peifeng, Budisavljevic, Milos N., Baicu, Catalin F., Zile, Michael R., Megyesi, Judit, Janech, Michael, Kwon, Sang-Ho, Collier, Justin, Schnellmann, Rick G., Nihalani, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708766/
https://ncbi.nlm.nih.gov/pubmed/31262488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.03.023
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