Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury.

Podocytes have limited ability to recover from injury. Here, we demonstrate that increased mitochondrial biogenesis, to meet the metabolic and energy demand of a cell, accelerates podocyte recovery from injury. Analysis of events induced during podocyte injury and recovery showed marked upregulation...

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Bibliografske podrobnosti
izdano v:Kidney Int
Main Authors: Arif, Ehtesham, Solanki, Ashish K., Srivastava, Pankaj, Rahman, Bushra, Fitzgibbon, Wayne R., Deng, Peifeng, Budisavljevic, Milos N., Baicu, Catalin F., Zile, Michael R., Megyesi, Judit, Janech, Michael, Kwon, Sang-Ho, Collier, Justin, Schnellmann, Rick G., Nihalani, Deepak
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708766/
https://ncbi.nlm.nih.gov/pubmed/31262488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.03.023
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