Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury.

Podocytes have limited ability to recover from injury. Here, we demonstrate that increased mitochondrial biogenesis, to meet the metabolic and energy demand of a cell, accelerates podocyte recovery from injury. Analysis of events induced during podocyte injury and recovery showed marked upregulation...

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Bibliographic Details
Published in:Kidney Int
Main Authors: Arif, Ehtesham, Solanki, Ashish K., Srivastava, Pankaj, Rahman, Bushra, Fitzgibbon, Wayne R., Deng, Peifeng, Budisavljevic, Milos N., Baicu, Catalin F., Zile, Michael R., Megyesi, Judit, Janech, Michael, Kwon, Sang-Ho, Collier, Justin, Schnellmann, Rick G., Nihalani, Deepak
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708766/
https://ncbi.nlm.nih.gov/pubmed/31262488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.03.023
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