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Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury
Aminopeptidase A (APA) is expressed in glomerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a peptide known to promote glomerulosclerosis. In this study, we tested whether APA expression changes in response to progressive nephron loss or whether APA exerts a protective...
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| Publicado no: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491295/ https://ncbi.nlm.nih.gov/pubmed/28202497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016111166 |
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