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Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface

Current assumption for assessing carcinogenic risk of polycyclic aromatic hydrocarbons (PAHs) is that they function through a common mechanism of action; however, recent studies demonstrate that PAHs can act through unique mechanisms potentially contributing to cancer outcomes in a non-additive mann...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Chang, Yvonne, Siddens, Lisbeth K., Heine, Lauren K., Sampson, David A., Yu, Zhen, Fischer, Kay A., Löhr, Christiane V., Tilton, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708476/
https://ncbi.nlm.nih.gov/pubmed/31255691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.114644
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