An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

Classical type 1 dendritic cells (cDC1s) are required for anti-viral and anti-tumor immunity, which necessitates an understanding of their development. Development of the cDC1 progenitor requires an E protein–dependent enhancer located 41 kilobases downstream of the transcription start site of the t...

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Bibliographic Details
Published in:Nat Immunol
Main Authors: Bagadia, Prachi, Huang, Xiao, Liu, Tiantian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschke, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707889/
https://ncbi.nlm.nih.gov/pubmed/31406377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0449-3
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