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Quality of TCR signaling encoded by differential enhancer affinities for the composite BATF-IRF4 transcription factor complex
Variable strengths of T cell receptor (TCR) signaling can produce divergent outcomes, but the mechanism remains obscure. The abundance of the transcription factor IRF4 increases with TCR signal strength, but how this would induce distinct types of responses is unclear. We compared T(H)2 gene express...
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| Veröffentlicht in: | Nat Immunol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5401770/ https://ncbi.nlm.nih.gov/pubmed/28346410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3714 |
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