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AAV-encoded Ca(V)2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain
Transmission of pain signals from primary sensory neurons to secondary neurons of the central nervous system is critically dependent on presynaptic voltage-gated calcium channels. Calcium channel-binding domain 3 (CBD3), derived from the collapsin response mediator protein 2 (CRMP2), is a peptide ap...
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| Publicado no: | Gene Ther |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707887/ https://ncbi.nlm.nih.gov/pubmed/31118475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-019-0082-7 |
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