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Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion
The Ca(2+) channel-binding domain 3 (CBD3) peptide, derived from the collapsin response mediator protein 2 (CRMP-2), is a recently discovered voltage-gated Ca(2+) channel (VGCC) blocker with a preference for Ca(V)2.2. Rodent administration of CBD3 conjugated to cell penetrating motif TAT (TAT-CBD3)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881029/ https://ncbi.nlm.nih.gov/pubmed/24152582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.56 |
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