Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

Pioneer transcription factors are characterized by having the unique property of enabling the opening of closed chromatin sites, for implementation of cell fates. We previously found that the pioneer Pax7 specifies melanotrope cells through deployment of an enhancer repertoire, which allows binding...

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發表在:Nat Commun
Main Authors: Mayran, Alexandre, Sochodolsky, Kevin, Khetchoumian, Konstantin, Harris, Juliette, Gauthier, Yves, Bemmo, Amandine, Balsalobre, Aurelio, Drouin, Jacques
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707328/
https://ncbi.nlm.nih.gov/pubmed/31444346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11791-9
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