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Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
Pioneer transcription factors are characterized by having the unique property of enabling the opening of closed chromatin sites, for implementation of cell fates. We previously found that the pioneer Pax7 specifies melanotrope cells through deployment of an enhancer repertoire, which allows binding...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707328/ https://ncbi.nlm.nih.gov/pubmed/31444346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11791-9 |
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