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Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

Translation is a basic cellular process and its capacity is adapted to cell function. In particular, secretory cells achieve high protein synthesis levels without triggering the protein stress response. It is unknown how and when translation capacity is increased during differentiation. Here, we sho...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Khetchoumian, Konstantin, Balsalobre, Aurélio, Mayran, Alexandre, Christian, Helen, Chénard, Valérie, St-Pierre, Julie, Drouin, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722061/
https://ncbi.nlm.nih.gov/pubmed/31481663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11894-3
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