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Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2

Translation is a basic cellular process and its capacity is adapted to cell function. In particular, secretory cells achieve high protein synthesis levels without triggering the protein stress response. It is unknown how and when translation capacity is increased during differentiation. Here, we sho...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Khetchoumian, Konstantin, Balsalobre, Aurélio, Mayran, Alexandre, Christian, Helen, Chénard, Valérie, St-Pierre, Julie, Drouin, Jacques
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722061/
https://ncbi.nlm.nih.gov/pubmed/31481663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11894-3
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