Pax7 pioneer factor action requires both paired and homeo DNA binding domains

The pioneer transcription factor Pax7 contains two DNA binding domains (DBD), a paired and a homeo domain. Previous work on Pax7 and the related Pax3 showed that each DBD binds a cognate DNA sequence, thus defining two targets of binding and possibly modalities of action. Genomic targets of Pax7 pio...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Pelletier, Audrey, Mayran, Alexandre, Gouhier, Arthur, Omichinski, James G, Balsalobre, Aurelio, Drouin, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287922/
https://ncbi.nlm.nih.gov/pubmed/34197620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab561
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