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Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors

N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors that play an essential role in mediating excitatory neurotransmission in the mammalian central nervous system (CNS). Functional NMDARs are tetramers composed of GluN1, GluN2A-D, and/or GluN3A-B subunits, giving rise to a wide...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Skrenkova, Kristyna, Hemelikova, Katarina, Kolcheva, Marharyta, Kortus, Stepan, Kaniakova, Martina, Krausova, Barbora, Horak, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707325/
https://ncbi.nlm.nih.gov/pubmed/31444392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48845-3
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