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Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors

N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors that play an essential role in mediating excitatory neurotransmission in the mammalian central nervous system (CNS). Functional NMDARs are tetramers composed of GluN1, GluN2A-D, and/or GluN3A-B subunits, giving rise to a wide...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Skrenkova, Kristyna, Hemelikova, Katarina, Kolcheva, Marharyta, Kortus, Stepan, Kaniakova, Martina, Krausova, Barbora, Horak, Martin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707325/
https://ncbi.nlm.nih.gov/pubmed/31444392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48845-3
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