Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors

N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors that play an essential role in mediating excitatory neurotransmission in the mammalian central nervous system (CNS). Functional NMDARs are tetramers composed of GluN1, GluN2A-D, and/or GluN3A-B subunits, giving rise to a wide...

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Publicado en:Sci Rep
Main Authors: Skrenkova, Kristyna, Hemelikova, Katarina, Kolcheva, Marharyta, Kortus, Stepan, Kaniakova, Martina, Krausova, Barbora, Horak, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707325/
https://ncbi.nlm.nih.gov/pubmed/31444392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48845-3
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