Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors

N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors that play an essential role in mediating excitatory neurotransmission in the mammalian central nervous system (CNS). Functional NMDARs are tetramers composed of GluN1, GluN2A-D, and/or GluN3A-B subunits, giving rise to a wide...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Skrenkova, Kristyna, Hemelikova, Katarina, Kolcheva, Marharyta, Kortus, Stepan, Kaniakova, Martina, Krausova, Barbora, Horak, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707325/
https://ncbi.nlm.nih.gov/pubmed/31444392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48845-3
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