Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non–Small Cell Lung Cancer: A Phase 1/2 Trial

IMPORTANCE: Local failure after chemoradiotherapy (CT-RT) significantly contributes to mortality in patients with locally advanced non–small cell lung cancer (LA-NSCLC). One approach to improve local control is through targeted radiosensitization of the tumor. OBJECTIVE: To evaluate the dose-limitin...

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Bibliographic Details
Published in:JAMA Oncol
Main Authors: Rengan, Ramesh, Mick, Rosemarie, Pryma, Daniel A., Lin, Lilie Leming, Christodouleas, John, Plastaras, John P., Simone, Charles B., Gupta, Anjali K., Evans, Tracey L., Stevenson, James P., Langer, Corey J., Kucharczuk, John, Friedberg, Joseph, Lam, Sarah, Patsch, Dana, Hahn, Stephen M., Maity, Amit
Format: Artigo
Language:Inglês
Published: American Medical Association 2019
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707020/
https://ncbi.nlm.nih.gov/pubmed/31436839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.2095
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