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Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non–Small Cell Lung Cancer: A Phase 1/2 Trial

IMPORTANCE: Local failure after chemoradiotherapy (CT-RT) significantly contributes to mortality in patients with locally advanced non–small cell lung cancer (LA-NSCLC). One approach to improve local control is through targeted radiosensitization of the tumor. OBJECTIVE: To evaluate the dose-limitin...

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Podrobná bibliografie
Vydáno v:JAMA Oncol
Hlavní autoři: Rengan, Ramesh, Mick, Rosemarie, Pryma, Daniel A., Lin, Lilie Leming, Christodouleas, John, Plastaras, John P., Simone, Charles B., Gupta, Anjali K., Evans, Tracey L., Stevenson, James P., Langer, Corey J., Kucharczuk, John, Friedberg, Joseph, Lam, Sarah, Patsch, Dana, Hahn, Stephen M., Maity, Amit
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707020/
https://ncbi.nlm.nih.gov/pubmed/31436839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.2095
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