Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non–Small Cell Lung Cancer: A Phase 1/2 Trial

IMPORTANCE: Local failure after chemoradiotherapy (CT-RT) significantly contributes to mortality in patients with locally advanced non–small cell lung cancer (LA-NSCLC). One approach to improve local control is through targeted radiosensitization of the tumor. OBJECTIVE: To evaluate the dose-limitin...

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Detalles Bibliográficos
Publicado en:JAMA Oncol
Main Authors: Rengan, Ramesh, Mick, Rosemarie, Pryma, Daniel A., Lin, Lilie Leming, Christodouleas, John, Plastaras, John P., Simone, Charles B., Gupta, Anjali K., Evans, Tracey L., Stevenson, James P., Langer, Corey J., Kucharczuk, John, Friedberg, Joseph, Lam, Sarah, Patsch, Dana, Hahn, Stephen M., Maity, Amit
Formato: Artigo
Idioma:Inglês
Publicado: American Medical Association 2019
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707020/
https://ncbi.nlm.nih.gov/pubmed/31436839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.2095
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