Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB

Mucopolysaccharide diseases (MPS) are caused by deficiency of glycosaminoglycan (GAG) degrading enzymes, leading to GAG accumulation. Neurodegenerative MPS diseases exhibit cognitive decline, behavioural problems and shortened lifespan. We have characterised neuropathological changes in mouse models...

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Bibliografische gegevens
Hoofdauteurs: Wilkinson, Fiona L., Holley, Rebecca J., Langford-Smith, Kia J., Badrinath, Soumya, Liao, Aiyin, Langford-Smith, Alex, Cooper, Jonathan D., Jones, Simon A., Wraith, J. Ed, Wynn, Rob F., Merry, Catherine L. R., Bigger, Brian W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338781/
https://ncbi.nlm.nih.gov/pubmed/22558223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035787
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