GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry

Selective gene delivery into subtypes of interneurons remains an important challenge in vector development. Adeno-associated virus (AAV) vector particles are especially promising for intracerebral injections. For cell entry, AAV2 particles are supposed to attach to heparan-sulfate proteoglycans (HSP...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Methods Clin Dev
Egile Nagusiak: Hartmann, Jessica, Thalheimer, Frederic B., Höpfner, Felix, Kerzel, Thomas, Khodosevich, Konstantin, García-González, Diego, Monyer, Hannah, Diester, Ilka, Büning, Hildegard, Carette, Jan E., Fries, Pascal, Buchholz, Christian J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706527/
https://ncbi.nlm.nih.gov/pubmed/31463334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.07.004
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